We provide molecular basis of inheritance practice exercises, instructions, and a learning material that allows learners to study outside of the classroom. We focus on molecular basis of inheritance skills mastery so, below you will get all questions that are also asking in the competition exam beside that classroom.
List of molecular basis of inheritance Questions
| Question No | Questions | Class |
|---|---|---|
| 1 | 140. In DNA, the linkages between different nitrogenous bases are (a) phosphate linkage (b) H-bonding (c) glycosidic linkage (d) peptide linkage. NECT |
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| 2 | What is a triplet codon? ( A ). Fixed B. Degenerate c. Ambiguous D. Non-wobbly |
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| 3 | The backbone of DNA is made up of? A. Sugar only B. Lipid and phosphate C. Protein and phosphate D. Sugar and phosphate |
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| 4 | Define transcription. | 12 |
| 5 | Choose the wrong statement in the process of protein synthesis. A. After uncoiling of DNA molecule, one strand acts as a template for the formation of mRNA. B. In the presence of DNA polymerase enzyme, the mRNA is formed based on the triplet codes. C. The mRNA that leaves nucleus reaches cytoplasm and gets attached with 30 S ribosomal subunit D. The amino acids are transferred from the intracellular amino acid pool to the active ribosomes by the tRNA. |
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| 6 | What is transcription? | 12 |
| 7 | Assertion Hn ( m R N A ) is larger than ( m R N A ) Reason Hn ( R N A ) has no translating introns and has more exons than required for translation. A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion c. Assertion is correct but Reason is incorrect D. Both Assertion and Reason are incorrect |
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| 8 | 133. The correct statement regarding RNA and DNA, respectively is (a) the sugar component in RNA is a arabinose and the sugar component in DNA is ribose the sugar component in RNA is 2′-deoxyribose and the sugar component in DNA is arabinose (C) the sugar component in RNA is arabinose and the sugar component in DNA is 2′-deoxyribose (d) the sugar component in RNA is ribose and the sugar component in DNA is 2′-deoxyribose. |
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| 9 | Choose the correct mRNA sequence for the given DNA sequence. AGTTCG A. TCUUGC B. UCAACG c. AGTTCG D. TCAACG E. UCAAGC |
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| 10 | Write any two chemical different between DNA and RNA. |
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| 11 | Antibiotic inhibiting interaction between tRNA and mRNA during protein synthesis in bacteria is A. Tetracycline B. Neomycin c. Erythromycin D. Streptomycin |
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| 12 | Draw a clover leat structure of tRNA showing the following. (i) Tyrosine attached to its amino acid site. (ii) Anticodon for this amino acid in its correct site (codon for tyrosine is UCA) |
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| 13 | How is this process of ( m R N A ) synthesis different from that in prokaryotes? |
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| 14 | Assertion: In prokaryotes, there are three initiation factors used for protein synthesis.
Reason: All the initiation factors have |
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| 15 | In one polynucleotide strand of a DNA molecule, the ratio of ( boldsymbol{A}+boldsymbol{T} / boldsymbol{G}+boldsymbol{C} ) is 0.3. What is the ( boldsymbol{A}+boldsymbol{G} / boldsymbol{T}+boldsymbol{C} ) ratio of the entire DNA molecule? A . 0.3 B. 0.6 c. 1.2 D. |
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| 16 | The structure of DNA and RNA are similar in that A. Both molecules are made of the same 5 carbon sugar. B. Both molecules are composed of the same four nitrogenous bases. C. The nucleotides of both molecules contain a phosphate group. D. Both molecules are double stranded which are antiparallel in directionality. |
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| 17 | Name the transcriptionally active region of chromatin in a nucleus. | 12 |
| 18 | Which of the following is translated completely? I. AUG, UGA, UUA, AAG, AAA II. AUG, AUA, UUG, CCC, UGA III. ( A G U, U C C, A G A, C U C, U A A ) IV. AUG, UAC, AGU, AAC, UAG A. I and II B. II and IV c. I and IV D. II and III |
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| 19 | Amino acid sequence, in protein synthesis is decided by the sequence of which one of the following? ( A cdot ) cDNA B. rRNA ( c cdot operatorname{tRNA} ) D. mRNA |
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| 20 | (a) Name the enzyme responsible for the transcription of tRNA and the amino acid the initiator tRNA gets linked with. (b) Explain the role of initiator tRNA in initiation of protein synthesis. |
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| 21 | According to lac operon concept, an operator gene combines with A. Co-repressor to switch off transcription of structural gene B. Inducer gene to switch on structural gene transcription C. Repressor gene to switch off transcription of structural gene D. Regulator protein to switch on structural gene transcription E. Regulator protein to switch off structural gene transcription |
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| 22 | A student is given two samples of nucleotides. One sample contains DNA nucleotides and the other sample contains RNA nucleotides, but the two samples have not been labeled. What information would assist the student in identifying which sample contained the DNA nucleotides versus the RNA nucleotides? A. The sugar in DNA nucleotides contains six carbon atoms and the sugar in an RNA molecule contains five carbon atoms. B. The sugar in DNA nucleotides is an aldehyde sugar anc the sugar in RNA nucleotides is a ketone sugar c. The sugar in DNA nucleotides contains one less oxyger atom than the sugar in RNA nucleotides D. The sugar in DNA nucleotides is in the alpha configuration and the sugar in RNA nucleotides is in the beta configuration |
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| 23 | Among the nitrogenous base involved in DNA and RNA formation, which is the double ring base? A. Uracil B. Guanine c. Thymine D. Cytosine |
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| 24 | What are termination codons? | 12 |
| 25 | Define a gene? | 12 |
| 26 | In the DNA molecule A. The proportion of adenine in relation of thymine varies with the organism. B. There are two strands which run antiparallel one in ( 5^{prime} ) ( rightarrow 3^{prime} ) direction and other in ( 3^{prime} rightarrow 5 ) C. The total amount of purine nucleotides and pyrimidine nucleotides is not always equal. D. There are two strands which run parallel in the ( 5^{prime} rightarrow 3^{prime} ) direction. |
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| 27 | Nucleosome core is intimately associated with A . 160 bp DNA B. 210 bp DNA c. 250 bp DNA D. 100 pp DNA |
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| 28 | The DNA model proposed by Watson and Crick A. combined many of the findings of other researches also studying DNA such as Rosalind Franklin and Chargaff. B. showed the double helix nature of the molecule C. presented a molecule with sugar-phosphate backbones on the outside and paired bases on the inside D. all of the above |
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| 29 | Describe the interaction of ( t-R N A, m ) RNA and ribosomes during the events of translation. |
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| 30 | The ( 3^{prime}-5^{prime} ) phosphodiester linkages inside a polynucleotide chain serve to join A. one nucleotide with the another nucleotide B. One nucleoside with another nucleoside c. one deoxyribose sugar with another nucleoside D. One nitrogenous base with pentose sugar |
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| 31 | During transcription, holoenzyme RNA polymerase binds to DNA sequence and DNA assumes a saddle like structure at that point. The sequence is called as ( A ). AAAT box B. TATA box ( c cdot operatorname{GGCC} ) box D. CAAT box |
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| 32 | The first amino acid formed during translation A. Occupies the aminyl site first, then the peptidyl site B. Occupies the aminyl site before the attachment of the large portion of the ribosome C. Of the polypeptide chain is methionine D. All of the above E. None of the above |
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| 33 | A eukaryotic gene contains two kinds of base sequences.Which of these plays an important role in protein synthesis? A. Introns B. Exons c. Both A and B D. None of the above |
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| 34 | The two polynucleotide chain in DNA are: A. Semiconservative B. Parallel c. Discontinuous D. Antiparallel |
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| 35 | Which of the following amino acid has hydroxyl methyl group as its R group? A. Serine B. Proline c. Alanine D. Arginine |
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| 36 | Which of the following enzyme is used to join DNA fragments? A. Terminase B. Endonuclease c. Ligase D. DNA polymerase |
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| 37 | Which of the following is an initiation codon? A . AUGGGGGGGGG ( . ) GGGGG B. UAG c. UGA D. UAA |
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| 38 | In Lac operon if a mutation occurs in the middle gene of the structural genes then A. ( beta ) – galactosidase will not be synthesised B. Permease will not be synthesised c. Transacetylase will not be synthesized D. Lactose digestion will be rapid |
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| 39 | The transcription unit extends from A. TATA box to start point B. TATA box to stop codon C . Start point to stop codon D. 35 sequence to start point |
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| 40 | How many among the following organisms hve linear ds DNA as their genetic material? Homo sapiens, Escherichia coil Drosophila, ( phi times 174 ) bacteriophage A . 1 B. 4 ( c .3 ) D. |
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| 41 | Match the enzyme in column I with its function in column II. |
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| 42 | Transfer of DNA bands from an agarose gel to a nitrocellulose or nylon membrane is referred to as A. western transfer B. Northern transfer c. Eastern transfer D. Gene transfer E. Southern blotting |
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| 43 | Watson and Crick were awarded Nobel Prize for their finding of A. RNA is single stranded B. DNA is double stranded c. DNA is genetic material D. DNA guides mRNA synthesis |
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| 44 | What is the process of joining together different DNA fragments often referred as? A. Transcription B. Cloning c. Gene splicing D. DNA amplification |
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| 45 | Protein synthesis commences when A. mRNA binds to the smaller subunit of Ribosomes B. mRNA bind to the larger subunit f Ribosome C. Both smaller and larger sub units binds each other over the mRNA molecule. D. The adapter RNA recognises the enzymes from cytoplasm. |
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| 46 | For the structure of nucleic acid, which of the following statements is wrong? A. DNA can be single stranded in some viruses. B. RNA can be double stranded occasionally. C. There are as many as 12 bases per turn in Z DNA. D. The length of one helix is ( 45 AA ) in B-DNA and in Z-DNA. |
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| 47 | Transcription means synthesis of A. DNA B. Protein c. mRNA D. Enzyme |
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| 48 | Using the given indicators, construct RNA nucleotide and any one DNA nucleotide. ( G ) hosphat |
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| 49 | A DNA molecule that recognizes specific transcription factors that can stimulate transcription of nearby genes is depicted by A. Promoter B. Enhancer c. operator D. Euchromatin E. Heterochromatin |
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| 50 | The enzyme required for transcription is A. Restriction enzyme B. DNA polymerase c. RNA polymerase D. RNase |
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| 51 | Choose the correct answers from the alternatives given : Which of the following regarding DNA is not true? A. Complementary base pairs consist of one purine and one pyrimidine B. Side rails of the DNA double helix are made of alternating molecules of phosphate and ribose c. complementary base pairs are joined by hydrogen bonds D. Amount of thymine equals the amount of adening |
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| 52 | Choose the correct answer from the alternatives given. Which of these is mismatched? A. Post transcriptional control-nucleus B. Translational control – cytoplasm c. Transcriptional control – -nucleus D. Postranslational control – nucleus |
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| 53 | Nucleoside is A. Nitrogenous base + sugar B. Nitrogenous base + sugar + phosphate c. sugar + phosphate D. Nitrogenous base + phosphate |
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| 54 | Assertion Replication and transcription occur in the nucleus but translation occurs in the cytoplasm. Reason mRNA is transferred from the nucleus into the cytoplasm where ribosomes and amino acids are available for protein synthesis. A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion. B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion C. Assertion is correct but Reason is incorrect. D. Both Assertion and Reason are incorrect. |
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| 55 | Histone occupies the major grooves of DNA at an angle of ( A cdot 15^{circ} ) B. ( 90^{circ} ) ( mathrm{c} cdot 45^{circ} ) to the helix axis D. 30 to the helix axis |
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| 56 | Genetic information in a DNA molecule is coded by the A. Sequence of nucleotides B. Base pairing c. Turning pattern of the helix D. Proportion of each base present |
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| 57 | The following ratio is generally constant for a given species :- ( A cdot T+C / G+A ) B. ( G+C / A+T ) c. ( A+C / T+G ) D. A + G / C +T |
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| 58 | Who among the following did not provide experimental proof for the semiconservative model of DNA replication? A. Meselson & Stahl B. Cairns c. Watson & Crick D. Taylor |
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| 59 | Why does synthesis of DNA proceed only in the ( 5^{prime} ) to ( 3^{prime} ) direction? A. DNA polymerases can only add nucleotides to the ( 3^{prime} ) end of a polynucleotide strand. B. The ( 3^{prime} ) end of the polynucleotide molecule is more electronegative than the ( 5^{prime} ) end. c. This is the direction in which the two strands of DNA unzip D. The chromosomes are always aligned in the ( 5^{prime} ) to ( 3^{prime} ) direction in the nucleus |
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| 60 | Ribose sugar differs from deoxyribose in having A. two extra oxygen molecules B. one extra oxygen molecules c. no oxygen D. Hydroxyl group |
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| 61 | mRNA coded language is known as A. Cryptogam B. Cryptoanalysis c. cryptogram D. codogens |
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| 62 | During protein synthesis in an organism, at one point the process comes to a halt. Select the group of the three codons from the following from which any one of the three could bring about this halt? A. UUU, UCC, UAU B. UUC, UAC c. UAG, UGA, UAA D. UUG, UCA, UCG |
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| 63 | In a typical DNA molecule, the proportion of thymine is ( 30 % ) of the ( mathrm{N} ) bases. Find out the percentages of other N bases. | 12 |
| 64 | What acts as an inducer in lac operon? How does it switch on the operon? | 12 |
| 65 | Transcription is the transfer of genetic code from a DNA molecule to A. RNA molecule B. Second DNA molecule C. Ribosomal sub unit D. Sequence of amino acids in a protein molecule |
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| 66 | One of these is not associated with termination of protein synthesis A. UAA B. UAG c. UGA D. AUGGGGGGGGG |
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| 67 | Lactose operon is considered to be glucose sensitive due to A. Catabolite induction B. Allosteric inhibition c. Anabolic inhibition D. None of the above |
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| 68 | The proportion of nucleotides in a given acid are : adenine 18%, Guanine 30%, Cytosine42 % and Uracil 10 %. Name the nucleic acid and mention the number of strands in it. |
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| 69 | Join properly Column-I and Column-II. Column I Column II ( (A) ) (1) Lysin A) UUU ( 6^{G C} ) (B) (2) Stop codon ( (C) ) (3) Phenyl Alanine AAA (D) (4) UAA Glycine ne ( A cdot a-2, b-3, c-4, d-1 ) B. ( a-4, b-3, c-1, d-2 ) c. ( a-1, b-4, c-3, d-2 ) D. ( a-3, b-4, c-1, d-2 ) |
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| 70 | First codon of uracil nucleotides, UUU was deciphered by A. Mathaei B. Khorana c. Nirenberg D. Both A and C |
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| 71 | Genetic code is a translation of the language of A. RNA into that of proteins B. Proteins into that of RNA c. Amino acids into that of RNA D. RNA into that of DNA |
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| 72 | Which component is not directly involved in the process known as translation? A. Ribosomes B. tRNA c. DNA D. mRNA |
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| 73 | Antiparallel strands of a DNA molecule means that A. One strand turns anti-clockwise B. The phosphate groups of two DNA strands, at their ends, share the same position. c. The phosphate groups at the start of two DNA strands are in opposite position (pole). D. One strand turns clockwise. |
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| 74 | DNA separated from one cell,when introduced into another cell is able to bestow some of the properties of former to the latter.What is this change called in technical terms? Describe the experimental evidences which led to the discovery of the above phenomenon. |
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| 75 | Which one of these substances will repress the lac operon? A. Arabinose B. Glucose c. Lactose D. Tryptopham |
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| 76 | Choose the correct answers from the alternatives given : During protein synthesis, an anticodon on transfer RNA (tRNA) pairs with A. messenger RNA (mRNA) nucleotide bases B. ribosomal RNA (rRNA) nucleotide bases c. other tRNA nucleotide bases D. DNA nucleotide bases |
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| 77 | Explain the double helix structure of DNA with a labelled diagram. | 12 |
| 78 | Purines possess nitrogen at which position? A. 1,2,4 and 6 position B. 1, 3, 5 and 7 position c. 1,3,7 and 9 position D. 1,2,6 and 8 position |
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| 79 | Which of the following statements about histones is not true? A. Histones are very similar between species B. Histones have many basic amino acids C. Histones are rich in lysine and arginine D. Each histone has one single gene that codes for it |
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| 80 | Explain Watson and Crick’s model of DNA. |
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| 81 | Match the columns. ( mathbf{A} ) ( a-2, b-3, c-1, d-4 ) B. ( a-1, b-4, c-2, d-3 ) c. ( a-3, b-1, c-4, d-2 ) D. ( a-2, b-4, c-1, d-3 ) |
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| 82 | Which one of the following statement is not correct? During protein synthesis, A. UAA codon codes for lysine. B. UGG codon codes for tryptophan. c. cysteine is coded by UGU and UGC codons. D. Tyrosine is coded by UAU and UAC |
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| 83 | DNA-dependent RNA polymerase catalyze transcription on one strand of the DNA which is called the A. Alpha strand B. Antistrand c. Template strand D. coding strand |
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| 84 | tRNA has the function of A. Transcription B. Carrier for attaching amino acids over mRNA template c. Transferring information to mRNA D. Carrying genetic code to cytoplasm |
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| 85 | The above-given model of t-RNA was explained by A. Watson and crick B. Friedrick meischer c. Clover leaf None of the above |
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| 86 | Discuss with your teacher and find out how to distinguish between. (a) Plasmid DNA and Chromosomal DNA (b) RNA and DNA (c) Exonuclease and Endonuclease |
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| 87 | The number of cytosine bases in a DNA molecule is equal to the number of bases. |
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| 88 | A short length linear double-stranded DNA molecule has 110 thymine and 110 guanine bases. The total number of nucleotide in the DNA fragment will be A . 110 B. 880 ( c cdot 440 ) D. 220 |
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| 89 | The process of RNA formation from DNA is called as A. Transition B. Translation c. Transversion D. Transcription |
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| 90 | Given below are the steps of protein synthesis. Arrange them in. correct sequence and select the correct option. (j) Codon-anticodon reaction between mRNA and aminoacyl tRNA complex. (ii) Attachment of mRNA and smaller sub-unit of ribosome. (iii) Charging or aminoacylation of tRNA. (iv) Attachment of larger sub unit of ribosome to the mRNA-tRNAMet complex. (v) Linking of adjacent amino acids. (vi) Formation of polypeptide chain. A ( cdot(text { ii }) rightarrow(i) rightarrow(text { iii }) rightarrow(v) rightarrow(text { iv }) rightarrow(v ) i) B. (v) ( rightarrow ) (ii) ( rightarrow(text { i) } rightarrow text { (iii) } rightarrow text { (iv) } rightarrow ) (vi) ( c cdot(text { iii) } rightarrow(text { ii) } rightarrow(text { iv }) rightarrow(i) rightarrow(v) rightarrow(v i) ) D. (iii) ( rightarrow(text { ii }) rightarrow(i) rightarrow(text { iv } v rightarrow(v) rightarrow(v i) ) |
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| 91 | Why is RNA required to undergo splicing? | 12 |
| 92 | Under electron microscope, chromatin fibres appear like beads in a string. The beads are A. Chromosomes B. Nucleosomes c. Solenoids D. Chromonemas |
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| 93 | A DNA segment has sequence ATC CAT CTA GTA, the sequence of RNA synthesized by this segment is A. TUG GTU GUT CAU в. GUT GтU GUT САU c. сАU ятบ яUт сти D. UAG GUA GAU CAU |
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| 94 | If a triplet on template DNA is AAA, what will be the anticodon on tRNA A. UUU B. AAA c. ( pi T ) D. AUGGGGGGGGGG |
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| 95 | Which of the following RNA’s picks up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis? ( mathbf{A} cdot ) tRNA B. mRNA c. rRNA D. All of the above |
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| 96 | Identify the protein with more than one polypeptide chain. A. Myoglobin B. Trypsin c. Immunoglobulin D. Lysozyme |
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| 97 | State the difference between the structural gene in a transcription unit of prokaryotes and eukaryotes. |
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| 98 | A smaller subunit of ribosome has a binding site for ( _{-}–_{-}- ) and the larger subunit has two binding sites for tRNA molecules. A ( cdot mathrm{Mg}^{+} ) B. Peptidyl transferase c. mRNA D. None of the above |
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| 99 | The helical structure of DNA was discovered by A. sanger B. Bloor c. L.Pauling D. watson and Crick |
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| 100 | Influence of genes in controlling the activity of living organisms is through A. Vitamins B. Protein synthesis c. Photosynthesis D. Hormones |
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| 101 | Initiation codon is A. UUU B. UGA c. AUG D. UAG |
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| 102 | Which of the following is utilized by all living organisms? A ( cdot C O_{2} ) B. A triplet genetic code to produce proteins c. oxygen D. ADP as cellular energy E. Membrane-bound organelles |
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| 103 | List two essential roles of ribosome during translation. |
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| 104 | Formation of RNA on DNA template is called as A. Transduction B. Transformation c. Transcription D. Translation |
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| 105 | The enzyme polynucleotide phosphorylase randomly assembles nucleotides into a polynucleotide phosphorylase to a solution of adenosine triphosphate and guanosine triphosphate, how many types artificial ( m R N A 3 ) nucleotide codons would be possible? ( mathbf{A} cdot mathbf{3} ) B. 4 c. 8 D. 16 |
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| 106 | The difference(s) between mRNA and tRNA is/are that: (i) mRNA has more elaborate 3 dimensional structure due to extensive base – pairing (ii) tRNA has more elaborate ( 3- ) dimensional structure due to extensive pairing (iii) tRNA is usually smaller than mRNA (iv) mRNA bears anticodon but tRNA has codons A. (i) and (iii) B. All of these c. (ii) and (iii) D. (i), (ii) and (iii) |
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| 107 | Which is most directly responsible for the sequence of amino acids in a protein? A. Sequence of the anticodons B. Number of codons in mRNA c. Proteins associated with rRNA D. The sequence of codons in mRNA |
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| 108 | ‘Abirin’ and ‘ricin’ are toxic plant proteins which inhibit the protein synthesis in eukaryotic ribosomes by inactivating the A. 40 s subunit B. 60S subunit ( c cdot 60 s ) and ( 40 S ) D. Genetic code |
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| 109 | The process of mRNA synthesis on a DNA is known as A. Translation B. Transcription c. Transduction D. Transformation |
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| 110 | In the light of Watson and Cricks model, describe the detailed structure of DNA. | 12 |
| 111 | Who proposed the ‘signal hypothesis’ meant for the biosynthesis of secretory type of proteins? A. Baltimore B. Camillio Golgi c. Blobel and Sabatini D. Sheeler and Bianchi |
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| 112 | Degeneration of genetic code is due to A. First member of codons B. Second member of codons c. Third member of codons D. Entire codons |
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| 113 | Match the following and choose the correct combination from the options given. ( begin{array}{llll} & text { Column-I } & & text { Column-II } \ text { A. } & begin{array}{l}text { Walter } \ text { Sutton }end{array} & text { 1. } & begin{array}{l}text { Discovered } \ text { penicillin }end{array} \ text { B. } & begin{array}{l}text { Thomas } \ text { Hunt }end{array} & text { 2. } & begin{array}{l}text { Discovered the } \ text { chromosomal } \ text { basis of heredity }end{array} \ text { D. } & begin{array}{l}text { James } \ text { Watson }end{array} & text { 3. } & begin{array}{l}text { Described the } \ text { phenomenon of } \ text { linkage and } \ text { crossing over }end{array} \ & text { Morgan } & & begin{array}{l}text { Discovered the } \ text { double helical } \ text { structure of DNA }end{array}end{array} ) A. A-1, B-4, C- 2, D-3 B. A- 2, B-3, C-1, D-4 C. ( A-3, B-2, C-1, D-4 ) D. A- 2, B-3, C-4,D-1 E. A- 4, B-1, C-2, ( D ) |
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| 114 | Ribosomes are sites of which reaction? A. Respiration B. Photosynthesis c. Protein synthesis D. Fat synthesis |
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| 115 | Watson and Crick are credited for the discovery that DNA A. Is a double stranded helì B. Is responsible for the synthesis of tRNA c. Is a carrier of genetic information D. Provides proof for the ( x ) -y chromosomal theory of sex determination |
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| 116 | The process involved in the RNA formation on the DNA template is called as A. Translation B. Transduction c. Transcription D. Transformaion |
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| 117 | Because most of the amino acids are represented by more than one codons, the genetic code is said to be A. Deaminated B. Comma less c. Degenerate D. Overlapping |
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| 118 | The pitch angle of deflection between two successive base pairs in DNA double helix is A ( cdot 20^{circ} ) B. ( 34^{circ} ) ( c cdot 36^{circ} ) D. ( 360^{circ} ) |
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| 119 | Antiparallel strands of a DNA molecule means that A. One strand turns clockwise. B. One strand turns anti-clockwise. C. The phosphate groups of two DNA strands at their ends share the same position. D. The phosphate groups at the start of two DNA strands are in opposite position (pole) |
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| 120 | During translation, activated amino acids get linked to (RNA). This process is commonly called as A. charging of tRNA B. discharging of tRNA c. aminoacylation of tRNA D. both (a) and (c). |
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| 121 | DNA is a polymer of nucleotides which are linked to each other by ( 3-5 ) phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose? A. Replace purines with pyrimidines. B. Remove/Replace 3 OH group in deoxyribose. c. Remove/Replace 2 OH group with some other group in deoxyribose. D. Both (b) and (c) |
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| 122 | B-DNA double helix makes a complete turn with A. Every 10 base pairss B. Every 20 base pairss C. Every 36 base pairs D. Every 3-6 base pairs |
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| 123 | The promoter site and the terminator site for transcription are located at ( A cdot 3 ) (downstream) end and 5 (upstream) end, respectively of the transcription unit B. 5 (upstream) end and 3 (downstream) end, respectively of the transcription unit C. the 5 (upstream) end D. the 3 (downstream) end. |
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| 124 | Which one of the following combinations is found in DNA ? A. Guanine and guanidine B. Guanidine and cytosine c. Guanine and cytosine D. Adenine and guanidine |
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| 125 | 137. The sequence of bases on RNA molecule synthesized on the GCATA strand of DNA is (a) CGUAU (b) CGTAT (c) TACGC (d) AYCGC (COMEDK) |
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| 126 | (a) Construct a complete transcription unit with promoter and terminator on the basis of the hypothetical template strand given below: (b) Write the RNA strand transcribed from the above transcription unit along with its polarity. |
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| 127 | What is aminoacylation? State its significance. | 12 |
| 128 | (a) Explain the experiment performed by Griffith on Streptococcus pneumoniae. What did he conclude from this experiment? (b) Name the three scientists who followed up Griffiths experiments. (c) What did they conclude and how? |
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| 129 | Method by which information reaches from DNA to RNA is A. Transcription B. Translation c. Transformation D. Transduction |
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| 130 | What is complementary base pairing? | 12 |
| 131 | How do histones acquire positive charge? | 12 |
| 132 | In ATG ACC AGG ACC CCA ACA sequence, the first base gets mutated. It will affect A. Change in types and sequence of amino acids B. Change in first amino acid only c. No change D. One amino acid less |
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| 133 | Adenine is ( 30 %, ) what would be the percentage of guanine? A . 10% B. 20% c. 30% D. 40% |
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| 134 | Length of DNA with 23 base pairs is A . ( 78.4 mathrm{A}^{circ} ) B. 78.2 A ( ^{text {о }} ) ( mathbf{c} cdot 78 mathrm{A}^{circ} ) D. 74.8 A |
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| 135 | Which one of the following pairs of codons is correctly matched with their function or the signal for the the particular amino acid? A. AUG, ACG – Start/methionine B. UUA, UCA – Leucine c. GUU – Alanine D. UAG, UGA – Stop |
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| 136 | Protein synthesis in an animal cell occurs A. Only on the ribosomes present in cytosol B. On ribosomes present in cytoplasm as well as in mitochondria C. Only on ribosomes attached to the nuclear envelope and smooth endoplasmic reticulum D. On ribosomes present in the nucleolus as well as in cytoplasm |
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| 137 | Which of the following is the pribnow box? A . 5′ TATAAT 3 B. 5′ TAATTAT 3 c. ( 5^{text {‘ }} ) AATAAT ( 3^{text {‘ }} ) D. 5′ ATATTA 3’ |
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| 138 | In a DNA molecule distance between two bases is ( mathbf{A} cdot 2 n m / 20 stackrel{circ}{A} ) B ( cdot 0.2 n m / 2 stackrel{circ}{A} ) c. ( 3.4 n m / 34^{circ} ) D. ( 0.34 n m / 3.4^{circ} ) |
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| 139 | Double-helical structure is found in | 12 |
| 140 | Teminism is same as A. Transcription B. Translation C. Reverse transcription D. DNA synthesis |
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| 141 | Choose the correct answer from the alternatives given: In E. Coli, the lac operon gets switched on when A. Lactose is present and it binds to the repressor B. Repressor binds to operator C. RNA polymerase binds- to the operator D. Lactose is present and it binds to RNA polymerase |
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| 142 | Portion of gene which is transcribed but not translated is ( A ). Exon B. Intron c. cistron D. codon |
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| 143 | A short length of DNA molecule has 80 thymine and 80 guanine bases. The total number of nucleotids in the DNA fragment is A ( cdot 160 ) B. 40 ( c cdot 80 ) D. 320 E. 640 |
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| 144 | Where are proteins synthesised inside the cell? |
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| 145 | The codon AUG has dual function. It is an initiation codon and also codes for A. Formaldehyde B. Methionine c. Phenylalanine D. serine |
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| 146 | Which one of the following codes for an amino acid? A. Cistron B. Exon c. codon D. Intron |
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| 147 | Termination of chain growth in protein synthesis is brought about by A. UUG, UGC, UCA B. UCG, GCG, ACC c. UAA, UAG, UGA D. UUG, UAG, UCG |
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| 148 | 67. The central dogma of molecular genetics states that the genetic information flows from (a) Amino acids Proteins DNA (b) DNA-Carbohydrates Proteins C) DNARNA Proteins (d) DNA RNA Carbohydrates (NEET Phase-I) |
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| 149 | Watson and Crick shared the Nobel Prize for DNA structure with A. Franklin B. Paulingg c. wilkins D. Tatum |
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| 150 | A DNA molecules measuring ( 680 A^{circ} ) contains |
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| 151 | Which of the following genes is not transcribed from the promoter for ( boldsymbol{beta} ) galactosidase? A . Lac- ( z ) B. Lac-i c. ( operatorname{Lac}-gamma ) D. Lac-A |
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| 152 | Wobble hypothesis deals with A. Phenomena of multiple codons coding for the code for a single amino acid B. Phenomena of multiple codons coding for the code for a different amino acid C. Phenomena of anticodon coding for the code for a different amino acid D. None of the above |
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| 153 | Which site of a tRNA molecule forms hydrogen bonds with mRNA molecule? A. codon B. Anticodon c. ( 5^{prime} ) end of the t-RNA molecule D. ( 3^{prime} ) end of the t-RNA molecul |
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| 154 | If the total amount of adenine and thymine in a double-stranded DNA is ( 45 % ), the amount of guanine in this DNA will be A . 22.5% B . 27.5% c. ( 45 % ) D. 55% |
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| 155 | If percentage of cytosine is ( 18 %, ) what will be the percentage of adenine? A . 32% B. 64% c. 36% D. 23% |
12 |
| 156 | The width of B-DNA is each turn of its helix has nucleotides. A. 34 A; 11 B. 20 ( dot{A} ; 12 ) c. ( 40 AA ; 8 ) D. ( 20 AA ; 10 ) |
12 |
| 157 | Write any four salient features of the Double helix structure of DNA. | 12 |
| 158 | The northern blot technique is used for the detection of A. Protein B. DNA c. RNA D. All of the above |
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| 159 | Match the components of lac operon of E. coli with their functions. Choose the answer with the correct combination of alphabets of the two columns. |
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| 160 | B-DNA which is right-handed double helix contains ( _{-1-} ) base pairs per turn of the helix and each turn is long. A. ( 10,3.4 AA ) B. 10,34 , c. ( 11,20 dot{A} ) D. 11,34 , ( dot{A} ) |
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| 161 | In genetic coding, triplet codons make possible 64 types of codons. If the genetic code was a doublet instead of a triplet codon, the number of types of codons possible would be A. 64 types of codons B. 4 types of codons c. 24 types of codons D. 16 types of codons |
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| 162 | In the processing of eukaryotic mRNA, during protein synthesis, tailing involves ………….. of RNA. A. Addition of adenylate residues at ( 3^{prime} ) end B. Addition of methyl guanosine triphosphate at ( 3^{prime} ) end C. Addition of methyl guanosine triphosphate at ( 5^{prime} ) end D. Removal of introns |
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| 163 | Influence of genes in controlling the activity of living organism is through A. Photosynthesis B. Protein synthesis c. Vitamins D. Hormones |
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| 164 | Which statement regarding translation is out of order first? A. Ribosomal subunits bind to mRNA B. Ribosome comes to a stop codon on the mRNA C. As a tRNA leaves the ribosome it passes its amino acid to the growing polypeptide D. The messenger RNA codon binds to the tRNA anticodon |
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| 165 | The number of base substitution possible in amino acid codons is A. 26 B. 264 ( c .535 ) D. 549 |
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| 166 | Which of the following is a function of nucleosome? A. It acts as a region of DNA transcription B. It holds RNA in position c. It helps in reducing the length of chromatin fibre D. All of the above |
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| 167 | DNA differs from RNA in having A. cytosine but no guanine B. Thymine but no uracil c. Uracil but no thymine D. Thymine but no cytosine |
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| 168 | The lac operon model is A. Inducible B. Repressible c. Both A and B D. Degenerate |
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| 169 | Identify the correct and incorrect statements. A. The four nucleotide bases are not necessarily present in DNA in exact equal proportions. B. The total amount of purines are equal to the total amount of pyrimidines. C. DNA ligase enzyme act to hydrolyse or breakdown a polynucleotide chain into its component nucleotides. D. Nuclease enzymes are capable of restoring an intact DNA duplex. A. B is correct but A, C and D are wrong B. A and B are wrong but C and D are correct c. ( A, B ) and ( C ) are correct but D is wrong D. A and B are correct but C and D are wrong E. B, C and D are correct but A is wrong |
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| 170 | Assertion Peptidyl transfer site is contributed by larger sub-unit of ribosome Reason The enzyme peptidyl transferase is contributed by both ( 23 S ) and 16 S ribosomal sub-units A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion c. Assertion is correct but Reason is incorrect D. Both Assertion and Reason are incorrect |
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| 171 | During transcription, holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called? A. CAAT box B. GGTT box C. AAAT box D. TATA box |
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| 172 | Describe the process of translation in Protein synthesis |
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| 173 | The coding strand of DNA is ( mathbf{5}^{prime} boldsymbol{A} boldsymbol{A} boldsymbol{T} boldsymbol{T} boldsymbol{C} boldsymbol{A} boldsymbol{A} boldsymbol{T} boldsymbol{T} boldsymbol{A} boldsymbol{G} boldsymbol{G} mathbf{3}^{prime} ) What is the sequence of mRNA? A . ( 3^{prime} )TTAAGTTTAATCC c. ( 3^{prime} ) ААUUСААUU АGG5 D. ( 5^{prime} )TTAAGTTTAATCC |
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| 174 | What is the length of human DNA containing ( 6.6 times 10^{9} ) bp nitrogen bases? ( mathbf{A} cdot 22 n m ) B. ( 0.22 mathrm{mm} ) ( mathbf{c} .2 .2 mathrm{m} ) D. 22m |
12 |
| 175 | If molecular weight of a polypeptide is ( 15.3 k D a, ) what would be the minimum number of nucleotides in the ( m R N A ) that codes for this polypeptide? Assume that molecule weight of each amino acid is 90 Da. A .510 в. 663 c. 123 D. 17 |
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| 176 | The process “translation” means A. DNA synthesis B. RNA synthesis c. Protein synthesis D. Ribosome assembly |
12 |
| 177 | Differentiate between nucleoside and nucleotide. |
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| 178 | Match the triplet codons mentioned in list I with their amino acids mentioned in listcolumn II and select the correct option from the given codes. |
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| 179 | DNA strands are anti-parallel because of A. H-bonds B. Phosphate diester bonds c. Disulphide bonds D. Peptide bonds |
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| 180 | During protein synthesis, amino acid gets attached to tRNA with the help of? ( A . ) mRNA B. Aminoacyl synthetase c. Ribosome D. rRNA |
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| 181 | Watson and Crick model of DNA is a A. ( B ) -form DNA with a spiral length of ( 34 AA ) and a diameter of ( 20 dot{A} ) B. ( A ) -form DNA with a spiral length of 15 and a diameter of ( 20 AA ) C. ( Z ) -form DNA with a spiral length of ( 34 AA ) and a diameter of ( 20 dot{A} ) D. ( B ) -form DNA with a spiral length of ( 28 dot{A} ) and a diameter of ( 14 dot{A} ) |
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| 182 | The Southern blot technique is used for the detection of A. DNA B. RNAA c. Protein D. RNA and DNA |
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| 183 | “It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for genetic material” – This is written by A. Meselson and Stahl B. Archibold Garrod c. severo ochoa D. watson and Crick |
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| 184 | The process of formation of mRNA from DNA is known as A. Transformation B. Translation c. Transcription D. Translocation E. Relication |
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| 185 | By using only one of the two strands of DNA, mRNA is produced this process is called as A. Transcription B. Translation c. Translocation D. Replacement |
12 |
| 186 | Wobble hypothesis for genetic code was given by A. Bernfield and Nirenberg B. Crick c. creighton D. Hedges |
12 |
| 187 | Choose the correct answer from the alternatives given The lac operon is transcribed when A. lactose is needed by the cell B. lactose is available to the cell c. lactose is unavailable to the cell D. lactic acid is available to the cell |
12 |
| 188 | The double helix model of Watson and Crick is known as A. C-DNA B. B-DNA c. z-DNA D. D-DNA |
12 |
| 189 | Find correct for both DNA and RNA A . Ability to replicate B. similar sugar c. similar bases D. Polymeric nucleotides |
12 |
| 190 | What is transcription? What are the different parts of a DNA transcription unit? What is their role in the process of transcription? |
12 |
| 191 | Mention two functions of the AUG. | 12 |
| 192 | Calculate the number of nitrogen bases in E.coli, if the length of E.coli DNA is 1.36 ( mathrm{mm} ) A ( cdot 4 times 10^{6} ) B. ( 8 times 10^{6} ) ( c cdot 2 times 10^{6} ) D. ( 16 times 10^{6} ) |
12 |
| 193 | Choose the correct answer from the alternatives given : If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is: ( 5-A ) T ( G A A T G-3 ) the sequence of bases in its RNA transcript would be A. 5-AUGAAUG-3 B. 5-UACUUAC-3 c. 5 сАUUсАU 3 D. 5-GUAAGUA-3. |
12 |
| 194 | What are the components of a nucleotide? |
12 |
| 195 | 81. The one letter code for the amino acid tryptophan is (a) G (b) V (c) W (d) H (e) A (Kerala PMT) |
12 |
| 196 | Proteins have primary structures. If you are given a method to know which amino acid is at either of two termini (ends) of a protein, can you connect this information to purity or homogeneity of a protein? |
12 |
| 197 | The triplet UUU codes for A. Leucine B. Methionine C. Phenyl alanine D. Glycine |
12 |
| 198 | Double helical structure of DNA was proposed by A. Kornberg B. Nirenberg c. watson and crick D. Wilkins and Franklin |
12 |
| 199 | 134. Which of the following is correct about H-bonding in DNA? (a) A-T, G-C (b) A—G,T-G (c) G-TA-C (d) A-AI-T |
12 |
| 200 | Find the nucleotide sequence of the MRNA which codes for the sequence of amino acids – ‘Met – Leu – Val – Arg – Ala’ and choose the correct option from below: A. AUG – GAU – GAA – UAU – UGU B. AUG – GAU – GAA – CGU – GCC c. AUG – CUA – GUG – UAU – UGU D. AUG – CUA – GUG – CGU – GCC |
12 |
| 201 | Choose the correct answer from the alternatives given: Identify the labels ( A, B, C ) and Din the |
12 |
| 202 | mRNA that carries information for complete polypeptide synthesis is A. Muton B. codon c. operon D. Reading frame |
12 |
| 203 | In a typical bacterial operon, where is an operator located to prevent transcription? A. Upstream of (before) the gene and the region of the promoter where RNA polymerase attaches. B. Downstream of (after) the gene and the region of the promoter where RNA polymerase attaches. C. At the location where the RNA polymerase attaches. D. Between the gene and the region of the promoter where RNA polymerase attaches. |
12 |
| 204 | Protein synthesis in an animal cell occurs A. Only on the ribosomes present in cytosol B. On ribosomes present in cytoplasm as well as in mitochondria c. only on ribosomes attached to the nuclear envelope and endoplasmic reticulum D. On ribosomes present in the nucleolus as well as in cytoplasm |
12 |
| 205 | Which enzyme plays important role in transcription? A. DNA dependent RNA polymerase B. DNA dependent DNA polymerase C. RNA dependent DNA polymerase D. RNA dependent RNA polyrnerase |
12 |
| 206 | In lac operon, structural gene ‘Z’ synthesizes A. ( beta ) – galactosidase B. Galactosidase permease c. Galactosidase transacetylase D. None of the above |
12 |
| 207 | The following picture depicts the DNA What is the structure of DNA ? A. Spherical B. Double Helix C. Dumbell D. Renal and longitudinal |
12 |
| 208 | Explain the significance of ‘palindromic nucleotide sequence’ in the formation of recombinant DNA. | 12 |
| 209 | Suppose evolution on earth has occurred in such a way that there are 96 amino acids instead of 20 DNA has 12 different types of bases and DNA synthesis occur in the same way as today.The minimum number of bases per DNA condon would be A ( cdot 12 ) B. 8 ( c cdot 2 ) D. 3 |
12 |
| 210 | Write the importance of DNA. | 12 |
| 211 | Which one of the following is the complementary sequence for the DNA with ( mathbf{5}^{prime} ) -CGTACTA-3′ ( ^{prime} ) A . ( 5^{prime} ) ‘-ТАGТАСG-3 B. 5′-ATCATGA-3 c. ( 5^{prime} ) -UTCUTGC-3′ D. 3′-GCATGAT-5’ |
12 |
| 212 | Given the fact that histone binds DNA, it should be rich in. A. Arginine, lysine B. Cysteine, methionine c. Glutamate, aspartate D. Isoleucine, leucine |
12 |
| 213 | Assertion Non-sense codon are responsible for termination of peptide chain. Reason Non-sense codons are not recognised by tRNA. A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion c. Assertion is correct but Reason is incorrect D. Both Assertion and Reason are incorrect |
12 |
| 214 | In E.coli, the chain initiating amino acid in protein synthesis is A. N-formyl methionine B. Methionine c. Glycine D. serine |
12 |
| 215 | Protein synthesis in an animal cell takes place A. Only in the cytoplasm B. In the cytoplasm as well as in mitochondria C. In the nucleolus as well as in the cytoplasm D. Only on ribose attached to nucleus |
12 |
| 216 | In order to produce many copies of a protein fast, the cell uses A. DNA replication B. single-unit ribosomes for high speed translation c. codon-anticodon reciprocal duplication D. many RNA polymerase molecules to produce mRNA transcripts at the same time |
12 |
| 217 | The bond formed between phosphate and pentose sugars of DNA is A. Sulphide bond B. Phosphodiester bond c. Hydrogen bond D. covalent bond |
12 |
| 218 | The enzyme peptidyl transferase of prokaryotes resides in A. 50 s ribosome B. 30s ribosome c. 40 s ribosome D. 60 ribosome |
12 |
| 219 | Technique for detecting and screening the nutritional mutants in Neurospora crassa was developed by A. Beadle and Tatum B. Bateson and Punnet c. Luria Dulbecco D. Knoll and Ruska |
12 |
| 220 | The nucleotide sequence on antisense strand of DNA which is transcribed as codon that specifies the amino acid serine is A. TCA B. AGUU c. TAC D. ccc |
12 |
| 221 | In the Watson and Crick model of DNA, the steps of the ladder are composed of A . sugars B. a purine and a pyrimidine c. two purines D. a sugar and a phosphate molecule |
12 |
| 222 | Association of m-RNA with several ribosomes is called A. Polysome B. Tranposons c. Both A and B D. None of the above |
12 |
| 223 | Choose the correct answer from the alternatives given : In a DNA strand the nucleotides are linked together by A. Glycosidic bonds B. Phosphodiester bonds c. Peptide bonds D. Hydrogen bonds |
12 |
| 224 | Degenerated DNA after heating can be studied by comparing A. A: T ratio B. G: C ratio c. sugar: phosphate D. Number of nucleotides |
12 |
| 225 | Which of the following is correct regarding genetic code? A. UUU is the initiation codon which also codes for phenylalanie. B. There are 64 triplet codons and only 20 amino acids. C. Three random nitrogen bases specify the placement of one amino acid. D. UAA is the nonsense codon which also codes for methionine. |
12 |
| 226 | What would happen if a recombinant DNA is inserted within the coding sequence of an enzyme, ( beta ) galactosidase? A. This will result in the inactivation of the enzyme B. The presence of chromogenic substrate will give blue coloured colonies c. The recombinant colonies do not produce any colour D. Both (1) and (3) are correct |
12 |
| 227 | Describe the process of synthesis of fully functional ( m R N A ) in a eukaryotic cell. |
12 |
| 228 | Q Type your question A DNA template plus primer with the structure ( 3 mathrm{P}-mathrm{TG} mathrm{C} ) GAATTAG ( mathrm{C} ) GACAT – PS ( 5 mathrm{P}-mathrm{ATCGGTACGACGCTTAAC} mathrm{OH} 3 ) (where ( P=a ) phosphate group) is placed in an in vitro DNA synthesis system containing ( M g^{2+}, ) an excess of the four deoxyribonucleoside triphosphates, etc. and a mutant form of E. Coli DNA polymerase I that lacks ( 5 rightarrow 3 ) exonuclease activity. The ( 5 rightarrow 3 ) polymerase and. ( 3 rightarrow 5 ) exonuclease activities of this aberrant enzyme are identical to those of normal E. Coli DNA polymerase I. It simply has no ( 5 rightarrow ) 3 exonuclease activity. What will be the structure of the final product? |
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| 229 | TAIPMT (Mains) ct when a phosphodiester 144. Find the hydrolysis product when a bond of nucleotide breaks. (a) 3-OH-deoxyribose-5-PO (b) 5-OH-deoxyribose-3-PO (c) 2-OH-deoxyribose-2-PO (d) 4-OH-deoxyribose-2-PO (All |
12 |
| 230 | During translation, if the codon on ( m ) RNA is AUG, then (i) What is the sequence of anticodon present on corresponding t-RNA? (ii) Name the amine acid carried by this t-RNA. |
12 |
| 231 | In a DNA molecule cytosine is ( 18 % ) Percentage of adenine would be A . 32% B. 64% c. 36% D. 18% |
12 |
| 232 | In split genes, the coding sequences are called as A. Introns B. Operons c. Exons D. Cistrons |
12 |
| 233 | mRNA directs the synthesis of proteins based on the sequence of A. Exons B. Introns c. codons D. Anticodons |
12 |
| 234 | SD region in prokaryotic mRNA is a part of A. TATA BOX B. RBS (Ribosome Binding Site) c. ASD region D. Promoter |
12 |
| 235 | Nucleosomes are not present in A . Plant B. Animal C. Bacteria D. Both A and B |
12 |
| 236 | Consider the following sequence on mRNA, AUGGCAGUGCCA. Assuming that genetic code is overlap then how many number of codon may be present on this genetic code? ( A cdot 9 ) B. 10 ( c cdot 8 ) D. 1 |
12 |
| 237 | Find the odd one out A. Transcription B. Transduction c. Translocation D. Mutation |
12 |
| 238 | 32. Genomic (DNA) studies in camel have been completed recently by the scientists of (1) South Africa (2) India (3) China (4) Pakistan |
12 |
| 239 | The inducer for switching on the lac operon in bacteria is A. Presence of lactos B. Number of bacteria c. Presence of structural genes in the bacteria D. Presence of sucrose E. Presence of RNA polymerase |
12 |
| 240 | Jacob and Monad studied lactose metabolism in E.Coli and proposed operon concept. Operon concept applicable for : – A. All prokaryotes B. All prokaryotes and some eukaryotes c. All prokaryotes and all eukaryotes D. All prokaryotes and some protozoanes |
12 |
| 241 | Identify the correct complementary base pairing among the following. A. Adenine – Thymine and Guanine – Cytosine B. Adenine – Guanine and Thymine – Cytosine c. Adenine – cytosine and Thymine – Guanine D. Guanine – Adenine and Cytosine – Adenine |
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| 242 | The enzyme which has polymerising activity in ( 5^{prime} rightarrow 3^{prime} ) direction but exonuclease activity in ( 3^{prime} rightarrow 5^{prime} ) direction only is : A. RNA polymerase III B. DNA polymerase II c. DNA polymerase D. All of these |
12 |
| 243 | Choose the correct answer from the alternatives given : Amino acids which are specified by single codons are A. Phenylalanine and arginine B. Tryptophan and methionine c. Valine and proline D. Methionine and arginine |
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| 244 | Which one is odd process? A. Translation B. Transformation c. Transduction D. conjugation |
12 |
| 245 | Write denaturing factors for proteins? | 12 |
| 246 | The peptide synthesis inside a cell takes place in A. Ribosomes B. Chloroplast c. Mitochondria D. chromoplast |
12 |
| 247 | The triplet on coding strand of DNA is ATG. What would be the required anticodon on corresponding tRNA during translation? A. UAA B. UAG c. UGA D. UACC |
12 |
| 248 | The nucleosomes are attached by ( mathbf{A} cdot ) SAT DNA B. Linker DNA c. Viral DNA D. None of the above |
12 |
| 249 | Which one of the following is not a structural part of a transcription unit in DNA? A. A promoter B. The structural gene c. The inducer D. A terminator |
12 |
| 250 | Which of the following is true of RNA, but not DNA? A. RNA contains ribose B. RNA contains adenine, guanine, cytosine and thymine c. RNA is usually double stranded D. RNA is produced using complementary base pairing |
12 |
| 251 | The one aspect, which is not a salient feature of genetic code, is its being A. Ambiguous B. Universal c. specific D. Degenerate |
12 |
| 252 | What is the function of non-histone protein? |
12 |
| 253 | If the length of DNA strand is ( 68 A^{circ} ) then, what will be the number of nucleotides present in DNA molecule A . 20 B. 40 ( c cdot 60 ) D. 80 |
12 |
| 254 | What will be the length of eukaryotic DNA segment having 10 pairs of nucleotides? |
12 |
| 255 | toppr LOGIN JOIN NOW ( widehat{n} ) Q Type your question ( – ) ( A cdot A-p, B-q, C-r, D-t, E-s ) B. ( A-r, B-p, C-t, D-s, E-q ) ( mathbf{C} ) 1 ( alpha ) – ( r, C-s, D-p, E-t ) 3- ( t, C-q, D-r, E-p ) ( D ) -1 ( E cdot A-t, B-s, C-p, D-q, E- ) |
12 |
| 256 | What will be the correct gene expression pathway? A. Gene-mRNA- transcription-translation-protein B. Transcription-Gene-translation-mRNA-protein C. Gene-transcription-mRNA-translation-protein D. Gene-translation-mRNA-transcription-protein |
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| 257 | Guanine pairs with A. Adenine B. Cytosine c. Thymine D. None of the above |
12 |
| 258 | In a DNA molecule, the phosphate group is attached to ( _{–} ) carbon of the sugar residue of its own nucleotide and ( _{-1-1} ) carbon of the sugar residue of the next nucleotide by bonds. A. 5 ‘, 3 ‘, phosphodiester B. 5′, 3’, glycosidic c. 3 ‘, 5′, phosphodiester D. 3′, 5’, glycosidic |
12 |
| 259 | What properties of the bacteriophages made them ideal material for solving the controversy regarding the genetic material to be protein or DNA ? |
12 |
| 260 | Which RNA carries information from DNA in protein synthesis? A. snRNA B. tRNA c. rRNA D. mRNA |
12 |
| 261 | Double helix model of DNA which was proposed by Watson and Crick was of A. C-DNA B. B-DNA c. D-DNA D. z-DNA |
12 |
| 262 | (a)Name the chemical that cements animal cells. (b)Name two contractile proteins. (c)What is the difference between RNA and DNA in their nitrogen bases. |
12 |
| 263 | Portion of gene, which is transcribed but not translated is? ( A ). Exon B. Intron c. cistron D. codon |
12 |
| 264 | The process of the formation of RNA from DNA is A. Transduction B. Transcription c. Transversion D. Transition |
12 |
| 265 | Collect 5 examples of palindromic sequence by consulting your teacher. Better try to create a palindromic sequence by following base-pair rules. | 12 |
| 266 | Name the parts ( a, b ) and ( c ) | 12 |
| 267 | Codon degeneracy means that A. Several of the amino acids are coded by more than one codon B. One codon can code for many amino acids C. One amino acid can be coded by only one codon. D. The codons are triplet nucleotide sequences. |
12 |
| 268 | What is a codon? How many codons serve as stop (non-sense) codons and how many as initiating codons? |
12 |
| 269 | Nucleosome contains ( mathbf{A} cdot H_{2} A, H_{2} B, H_{3}, H_{4} ) ( mathbf{B} cdot H_{3}, H_{4} ) ( mathbf{c} cdot H_{2} A, H_{2} B, H_{3} ) D. ( H_{1}, H_{2} A, H_{2} B, H_{3} ) |
12 |
| 270 | Rosalind Franklin produced an X-ray image that helped Watson and Crick determine the width of a DNA molecule. What did this information help them realize? A. Bonding between two purines would be consistent witt the diameter of the DNA helix B. Chargaffs Rule did not apply to the DNA molecule c. Bonding between a purine and pyrimidine would be consistent with this width of a DNA helix since each rung has a three-ring molecular dimension. D. Adenine must bond with cytosine, and guanine must bond with thymine on each rung of the DNA ladder to accommodate for proper diameter of the double helix |
12 |
| 271 | Structures called beads on string are A. Nucleosomes B. Base pairs c. Genes D. Nucleotides |
12 |
| 272 | Write the important features of genetic code. |
12 |
| 273 | Enlist the type of non-genetic RNA. What is a gene responsible for expression of a trait called? |
12 |
| 274 | Phosphorus is present in A. Protein B. DNA ( c . ) RNA D. Both DNA and RNA |
12 |
| 275 | Assertion A change in nitrogen base at the third position of a codon causes change in the expression of the codon. Reason A codon is mostly read by all the three nitrogen bases. A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion c. Assertion is correct but Reason is incorrect D. Both Assertion and Reason are incorrect |
12 |
| 276 | Melting temperature for double stranded molecules are converted into single stranded molecules. Which one of the following DNA will have the highest melting temperature? A. DNA with ( 15 % ) guanine B. DNA with 30% cytosine C. DNA with ( 40 % ) Thymine D. DNa with ( 50 % ) adenine |
12 |
| 277 | A codon is made up of A. single nucleotide B. Two nucleotides C. Three nucleotides D. Four nucleotides |
12 |
| 278 | DNA differs from RNA in having A. Uracil B. Thymine C. Adenine D. Guanine |
12 |
| 279 | Degeneration of a genetic code is attributed to the A. First member of a codon B. Second member of a codon c. Entire codon D. Third member of a codon |
12 |
| 280 | Sequencing of genomic DNA is included under A. Structural genomics B. Functional genomics c. Proteomics D. Transgenesis |
12 |
| 281 | Read carefully the sequence of codons in the mRNA unit and answer the questions. (a) What change is needed in the first codon to start the translation process? (b) If translation starts by that change, till which codon it can continuous? Why? |
12 |
| 282 | According to Watson-Crick model hydrogen bonding in a double-stranded DNA occurs between. A. Adenine and guanine B. Adenine and thymine. c. cytosine and adenine. D. Guanine and thymine. |
12 |
| 283 | In the double helix model of DNA as proposed by Watson and Crick, each base pair is how far from the next base pair? ( A cdot 0.034 mathrm{nm} ) B. 0.34 nm ( c .3 .4 mathrm{nm} ) D. 34 nm |
12 |
| 284 | DNA strands A. Have quaternary structure like protein B. Are bonded by disulphide bonds C. Have same polarity D. Are antiparallel |
12 |
| 285 | During the molecular functioning of genes, which process converts RNA into protein? A. Trancription B. Translation c. Transfection D. Transfusion |
12 |
| 286 | Template theory suggests A. Amino acids have to be activated B. Acylation C. Combination of amino acid with tRNA first D. All of the above |
12 |
| 287 | Who discovered genetic code? A. Nirenberg B. Khorana c. Ochoa D. Crick |
12 |
| 288 | Fill the columns and complete the given table. Give explanation for your answer |
12 |
| 289 | Define translocation. | 12 |
| 290 | Which of the following is a nucleoside? A. Adenosine B. Adenine c. Deoxyribose D. Adenylic acid |
12 |
| 291 | Correct sequence for Alanine code is A . GCU, GCC, GCA B. GAU, GAC, GAA c. AGU, AGC, AGA D. GUU, GUC, GUA |
12 |
| 292 | Genetic code consists of A. 4 codons, each with two nucleotides B. 16 codons, each with four nucleotides C. 64 codons, each with two nucleotides D. 64 codons, each with three nucleotides |
12 |
| 293 | Polysomes lack A. Proteins B. mRNA c. DNA D. tRNA and rRNA |
12 |
| 294 | In DNA replication, the primer is A. A small deoxyribonucleotide polymer. B. A small ribonucleotide polymer. C . Helix destabilizing protein. D. Enzyme taking part in joining nucleotides of new strand. |
12 |
| 295 | Which of the following is important for transcription? A. CAAT box B. Promoter c. RNA polymerase D. All of the above |
12 |
| 296 | Which of the following statements about nucleosome is true? A. It consists of only DNA. B. It is a nucleus-like structure found in prokaryotes c. It consists of DNA and proteins D. It consists of only histone proteins |
12 |
| 297 | Which of the following is not correct about translation? A. It starts with AUG. B. Stopped at termination codon c. Based on operon model. D. Occurs in nucleus |
12 |
| 298 | Which one of the following process occurs inside the nucleus during protein synthesis in a eukaryotic cells? A. Processing of hnRNA B. Activation of amino acids c. Translation D. Formation of polypeptide chain |
12 |
| 299 | Which codon does not have tRNA? A. Start codon B. Stop codon c. Aua D. GGG E. UUU |
12 |
| 300 | Variegated coloration of leaves, first studied by K.Correns in 1909 is inherited only from the female parent. The genes coding for this trait are located in A . ER B. Nucleus c. Plastids D. Plasma membrane |
12 |
| 301 | Which of the following is a transcription factor produced by a regulatory gene? A. A promoter B. An operon c. A cofactor D. A repressor |
12 |
| 302 | Assertion Transcription unit is often monocistronic in eukaryotes and polycistronic in prokaryotes. Reason Exons do not appear in mature RNA, introns appear in mature RNA. A. Assertion and Reason are true, Reason is correct explanation of Assertion. B. Assertion and Reason are true, Reason is not the correct explanation of Assertion C. Assertion is true, Reason is false. D. Assertion is false, Reason is true. |
12 |
| 303 | When a single anticodon can recognize more than one codon of mRNA it is called as A. Template hypothesis B. Degeneracy c. Gene flow hypothesis D. collinearity hypothesis |
12 |
| 304 | The following diagram shows a protein coding DNA and specifies the positions of its translational start and stop signals ( 5^{prime} . . . . . . . . mathrm{G} mathrm{AT} ldots . . . . . . . ) Which of the following statements with regard to template strand for the RNA polymerase and the C-terminus of the resulting protein is true? A. Upper is template strand, carboxy terminus of protein to right. B. Upper is template strand, carboxy terminus of protein to left C. Lower is temperate stand, carboxy terminus of protein to right. D. Lower is template strand, carboxy terminus of protein to left. E. Either strand could be a template on basis of this information |
12 |
| 305 | How many nucleotides in messenger RNA’s sequence makes a codon for an amino acid? A. Three B. Four c. one D. Two |
12 |
| 306 | What is nucleosome? Draw diagram of double stranded polynucleotide chain of DNA and explain its structure. | 12 |
| 307 | What is transformation? | 12 |
| 308 | Choose the correct answers from the alternatives given. What is the function of DNA ligase in recombinant technology? A. Cut DNA into many fragments B. Carry DNA into a new cell c. Link together newly joined fragments of DNA D. Separate fragments of DNA by their length and electrical charges |
12 |
| 309 | Termination of chain growth in protein synthesis is brought about by the codons A. UAA, UAG and UGA в. UCG, АСС аnd GсG c. UUG, UAG and UGA |
12 |
| 310 | DNA is associated with basic protein A. Albumin B. Non-histone c. Histone D. Both A and C |
12 |
| 311 | If DNA was made of 6 nucleotides instead of ( 4, ) what are the total number of triplet codons possible? A .24 B . 18 ( c .64 ) D. 216 |
12 |
| 312 | Which of the following is not produced by E.Coli in the lactose operon? A. ( beta ) galactosidase B. Galactoside transacetylase c. Lactose dehydrogenase D. Galactoside permease |
12 |
| 313 | What are introns? | 12 |
| 314 | Describe the experiment performed by Griffith. What conclusions did he infer from his observations? |
12 |
| 315 | Wobble hypothesis was proposed by A. Holley B. Nirenberg c. Khorana D. Crick |
12 |
| 316 | Production of a human protein in bacteria by genetic engineering is possible because A. Bacterial cell can carry out the RNA splicing reactions. B. The mechanism of gene regulation is identical in humans and bacteria c. The human chromosome can replicate in bacterial cell. D. The genetic code is universal |
12 |
| 317 | In genetics, a reference is made to an abbreviated expression AUG. Write any three points of scientific information embodied in this combination of three letters. |
12 |
| 318 | 36. Transcription means the synthe sis of (1) Lipids (2) Protein (3) DNA (4) RNA |
12 |
| 319 | Which among the equations of the nitrogenous base content in the DNA is not true? A ( cdot A+G=T+C ) B. ( A+T=G+C ) ( c cdot G=c ) |
12 |
| 320 | Explain the dual function of AUG codon. Give the sequence of bases it is transcribed from and its anticodon. | 12 |
| 321 | Which of the following inhibits protein synthesis by binding to 50S ribosome? A. Tetracycline B. Streptomycin c. Erythromycin D. Penicillin |
12 |
| 322 | DNA found in the nucleus is wrapped around a simple protein which is basic in nature. This protein is also thought to regulate DNA functioning find some way. Name this protein. A. Collagen B. Renin c. Pepsin D. Histones |
12 |
| 323 | Choose the correct order of the steps involved in protein synthesis and modification that takes place in several different locations throughout the cell. I. Ribosome II. Nucleus III. Golgi apparatus IV. Endoplasmic reticulum A . ।, ॥, III and IV B. ॥,।, IV and III c. ॥ा, ॥, Iv and । D. ॥, I, III and IV E . IV, III, II and I |
12 |
| 324 | Which of the following act as a substrate for an enzyme that charges tRNA molecules? I. Amino acid I. ATP III. tRNA IV. snRNA A. I only B. II only c. ॥ा only D. I, II, and III E . ।, ॥, ॥ा, and IV |
12 |
| 325 | Examine the data showing the percent identity of the GAPDH gene and protein sequences between humans and the three species shown below. Species G lo ( begin{array}{ll}text { Gene } & text { Protein } \ text { ldentity } & text { ldentity }end{array} ) 99.6% ( quad 100 % ) Chimpanzee Fruit Fly 72.4% 76.7% Roundworm ( 68.2 % ) 74.3% Provide a possible reason for why the percent identity between gene sequences is lower than the percent identity of protein sequences. A. Multiple codons code for the same amino acid B. Introns are likely to have different sequences. c. Differences in DNA sequences are edited when the mRNA is transcribed D. Amino acids cannot be substituted without consequence |
12 |
| 326 | A codon in mRNA has A. 3 bases B. 2 bases c. 1 base D. Number of bases vary |
12 |
| 327 | Assertion Histones are basic proteins of major importance in packaging of eukaryotic DNA. DNA and histones comprise chromatin forming the bulk of eukaryotic chromosome. Reason Histones are of five major types: ( mathrm{H} 1 ) H2A, H2B, H3 and H4. A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion. B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion C. Assertion is correct but Reason is incorrect. D. Both Assertion and Reason are incorrect. |
12 |
| 328 | State whether the following statements are true or false. All of the molecules available for biosynthesis constitute the metabolic pool A. True B. False |
12 |
| 329 | Differentiate between translation and translocation. |
12 |
| 330 | In the lac operon, the structural genes are switched off when repressor binds to the A. Operator B. Promoter c. Regulator D. Inducer E. Allolactose |
12 |
| 331 | Out of 64 codons only 61 codes for the 20 different amino acids. This character of genetic code is called as A. Degeneracy B. Non ambiguous nature c. Redundancy D. Overlapping |
12 |
| 332 | The chemical differences between DNA and RNA are A. DNA has deoxyribose sugar and RNA has ribose sugar B. DNA is double stranded and RNA is single stranded C. Nitrogenous bases are only present in DNA. D. Both A and B |
12 |
| 333 | In which of the following would you expect to find the most highly conserved sequences of nucleic acids? A. Structurally critical regions of a polypeptide such as an active site region B. The intron regions of pre-mRNA sequences C. Ribosomal RNA sequences D. Bacterial genes conferring antibiotic resistance |
12 |
| 334 | Describe Watson and Crick’s model of DNA. |
12 |
| 335 | How do ( m-R N A, t-R N A ) and ribosomes help in the process of translation? |
12 |
| 336 | An operon unit consist of A. Regulator, operator and recessive gene B. Regulator, structural and operator gene C. Regulator, structural, operator and promoter gene D. Regulator, structural and promoter gene |
12 |
| 337 | Read the statements 1 and 2 . Choose the correct option: Statement 1: RNAi take place in all prokaryotic and eukaryotic organisms as a method ofcellular defence. Statement 2: RNA interference is a pre- |
12 |
| 338 | Which one of the following is a base analogue? A. Nitrous acid B. Colchicine c. 5 – bromouracil D. Caffeine |
12 |
| 339 | Elongation of peptide chain involves all except ( A . ) mRNA B. GTP and peptidyl tranferase c. Tu, Ts and G factors D. Formyl met-tRNA |
12 |
| 340 | ( ln ) a 125 amino acid sequence, if ( 25^{t h} ) amino acid is mutated to UAA, then A. A polypeptide of 124 amino acids is formed. B. A polypeptide of 25 amino acids is formed c. A polypeptide of 24 amino acids is formed. D. Any of the above can be possible. |
12 |
| 341 | List the criteria a molecule that can act as genetic material must fulfill. Which one of the criteria are best fulfilled by DNA or by RNA thus making one of them a better genetic material than the other? |
12 |
| 342 | Due to deficiency of phosphorus. A. The rate of protein synthesis is increased B. The rate of protein synthesis is decreased C. There is no effect on the rate of protein synthesis D. The rate of protein synthesis initially declines but increases later on |
12 |
| 343 | Distinguish between DNA and RNA. | 12 |
| 344 | A gene encoding for polypeptide of 50 amino acids get mutated at 25 codon; UAU becoming UAA. The result would be A. Polypeptide of 24 amino acid B. Two polypeptides one with 24 amino acids and second with 25 amino acids c. A polypeptide with 49 amino acid D. A polypeptide of 25 amino acids |
12 |
| 345 | 132. What type of sugar molecule is present in DNA? (a) D-3-Deoxyribose (b) D-Ribose (C) D-2-Deoxyribose (d) D-Glucopyranose AUT |
12 |
| 346 | Ribosome in eukaryotes involves in A. Transformation B. Translation c. Transcription D. Translocation E. Replication |
12 |
| 347 | The anticodon found on the t-RNA for trytophan amino acid is A. ucc B. cuu c. АСС D. UGG |
12 |
| 348 | The tRNA anticodon 3-UAC-5 will pair with the mRNA codon A. 5-AUU-3 B. 5-UAC-3 c. 5-AUG-3 D. 3-GUA-5 |
12 |
| 349 | Choose the incorrect statement regarding DNA structure. A. Base stacking destabilise DNA double helical structure. B. Each chain in DNA constitute sugar-phosphate backbone C. Two chains are coiled in right handed fashion D. The pitch of the helix has roughly 10 bp. |
12 |
| 350 | Which one of the following group of codons is called as degenerate codons? A. UAA, UAG and UGA B. GUA, GUG, GCA and GCG C . UUC, UUG, CCU, CAA and CUG D. UUA and UUG, CUU, CUC and CUG E . AAC, AAG, GAC and CGG |
12 |
| 351 | The enzyme involved in transcription is A. RNA polymerase B. DNA polymerase I c. DNA polymerase II |
12 |
| 352 | Select the correct option regarding genetic code of Glycine. A. GUU, GUC, GUA B. GAU, GAC, GAA c. GGU, GGА, яGС D. GGU, GGA, GCU |
12 |
| 353 | Give reasons Genetic code is universal. | 12 |
| 354 | Identify the disadvantages of RNA over DNA as a genetic material and explain ¡t. | 12 |
| 355 | Which of the following is a sulphur containing amino acid A. Alanine B. Glycine c. Methionine D. valine |
12 |
| 356 | All of the following are involved in prokaryote protein synthesis except A. Introns are removed from the mRNA transcript B. RNA polymerase copies DNA into RNA nucleotides to produce mRNA C. Translation occurs simultaneously with transcription. D. Transcription and translation occur in the cytoplasm. E. All of the above events occur in prokaryote protein synthesis |
12 |
| 357 | Which of the following are associated with a consensus sequence and a signal sequence? A. Translation, hnRNAs B. DNA, translation c. Transcription, a snurp D. hnRNA, a snurp E. Spliceosomes, translation |
12 |
| 358 | What is the common point of similarity between DNA and RNA? A. Both are double stranded B. Both have identical sugar molecules c. Both have identical pyrimidine bases D. Both are polymers of nucleotides |
12 |
| 359 | Draw the schematic/diagrammatic presentation of the lac operon. | 12 |
| 360 | The mechanism of removing introns followed by joining of the exons in a defined order during transcription is called A. Splicing B. Tailing c. Transformation D. Capping |
12 |
| 361 | Nitrogenous base present in DNA are (a) Thymine (b) Cytosine (c) Adenine (d) Guanine ( A cdot a, b, c ) B. a, c, d ( c cdot b, c, d ) D. all |
12 |
| 362 | Which property of DNA double helix led Watson and Crick to hypothesise semiconservative mode of DNA replication? Explain. | 12 |
| 363 | Which of the following anticodon sequence will bind to the transcribed codon ( 5^{prime}-A C T-3^{prime} ? ) A . 3′-ACU-5′ B. 3′-TGA-5′ c. 3′-UGA-5′ D. 5′-UGA-3′ E. None of the above |
12 |
| 364 | In animal tissue culture which of the following radioactive nucleotide is used to measure RNA synthesis? A. Adenine B. Cytosine c. Guanine D. Thymine E. Uracil |
12 |
| 365 | Assertion Replication and transcription occur in the nucleus but translation takes place in the cytoplasm. Reason mRNA is transferred from the nucleus into cytoplasm where ribsomes and amino acids are available for protein synthesis. A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion C. Assertion is correct but Reason is incorrect D. Both Assertion and Reason are incorrect |
12 |
| 366 | E. coli cells with a mutated Z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because A. In the presence of glucose, E. coli cells do not utilize lactose B. They cannot transport lactose from the medium into the cell. c. The lac operon is constitutively active in these cells. D. They cannot synthesize functional ( beta ) -galactosidase. |
12 |
| 367 | Length of one loop of B DNA is ( A .3 .4 mathrm{nm} ) B. 0.34 nm ( c cdot 20 mathrm{nm} ) D. ( 10 mathrm{nm} ) |
12 |
| 368 | Consider these sentences regarding the structure and nature of DNA. I. DNA has two pyrimidine bases that contain single ring structure. II. In DNA, composition of bases should be ( frac{boldsymbol{A}+boldsymbol{T}}{boldsymbol{G}+boldsymbol{C}}=mathbf{1} ) III. Each base pair of DNA is ( 3.4 A ) apart from other base pairs. IV. The nucleosome model DNA packaging was proposed by Kornberg and Thomas. Choose the correct statements from the |
12 |
| 369 | Group the following as nitrogenous bases and nucleosides: Adenine, Cytidine, Thymine, Guanosine, Uracil and Cytosine. |
12 |
| 370 | Transcription unit A. starts with TATA box B. starts-with pallendrous regions and ends with rho factor C. starts with promoter region and ends in terminator region D. starts with CAAT region |
12 |
| 371 | What would be the molar concentration of human DNA in a human cell? Consult your teacher. |
12 |
| 372 | Which of the following is required as inducer(s) for the expression of Lac operon? A. Glucose B. Galactose c. Lactose D. Lactose and galactose |
12 |
| 373 | Which one of the following is a stop codon? A . UAGGGGGG B. UAC c. AUG D. UcA |
12 |
| 374 | Diagrammatically represent the experimental steps in cloning and expressing a human gene (say the gene for growth hormone) in a bacteria like ( E ) coli? |
12 |
| 375 | Which of the following statement is true about RNA? A. It contains adenine paired to thymine B. One of the bases from DNA is replaced by uracil C. It contains the sugar deoxyribose D. Its nucleotides contain twice as many phosphate groups as DNAs nucleotides |
12 |
| 376 | In a dsDNA number of phosphodiester bonds are 3250 , then find the number of base pairs. A. 1625 B. 1626 c. 3252 D. 3250 |
12 |
| 377 | UAA, UAG and UGA are A. Non overlapping codons B. Non sense codons C. Degenerate codons D. Chain initiator codons |
12 |
| 378 | Choose the correct answers from the alternatives given: Transcription is the transfer of genetic code from a DNA molecule to a A. RNA molecule B. Second DNA molecule c. Ribosomal subunit D. Sequence of amino acids in a protein molecule |
12 |
| 379 | Which of the following biologists has been dubbed as the architect of molecular biology? A. Francis Crick B. Frederick Sanger c. Jacques Lucien Monod D. James Watson |
12 |
| 380 | Sequence of amino acid in polypeptide chain is determined by ( A cdot r R N A ) B. sn RNA c. n RNA D. m RNA |
12 |
| 381 | Choose the correct answer from the alternatives given : An organism uses 20 amino acids while its DNA is made up of 6 types of nitrogenous bases. What would be the minimum size of a codon? ( A cdot 6 ) B. 4 ( c cdot 3 ) D. 2 |
12 |
| 382 | Which of the following organelle is responsible for differentiation? A. Nucleus B. Mitochondria c. Ribosomes D. Centrioles |
12 |
| 383 | Chloramphenicol prevents protein synthesis over A. Prokaryotic ribosomes B. Organelle ribosomes c. Both A and B D. 80 S ribosomes |
12 |
| 384 | The template for protein synthesis is A. DNA B. mRNA c. rRNA D. tRNA |
12 |
| 385 | A living cell is characterized by the presence of several cellular structures and molecular processes. The correct statement regarding living cells is A. The nucleus is a characteristic feature of all living cells B. An mRNA sequence is never completely represented in its translated product c. Anticodons are located on the rRNA D. splicing of introns in prokaryotes occurs in the cytoplasm |
12 |
| 386 | What is the width of DNA molecule? A ( cdot 15 mathrm{A}^{circ} ) B. 20 A ( ^{text {о }} ) c. ( 25 mathrm{A}^{circ} ) D. 34 A |
12 |
| 387 | Diameter of DNA double helix is ( A cdot 34 A^{0} ) B . 20 ( A^{0} ) c. ( 3.4 A^{circ} ) D. 340 ( A^{circ} ) |
12 |
| 388 | Which is the principal site for the development of ribosomal RNAs? | 12 |
| 389 | Assertion A monocistronic mRNA can produce several types of polypeptide chains. Reason The terminator codon is present on the mRNA. A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion c. Assertion is incorrect but Reason is correct D. Both Assertion and Reason are incorrect |
12 |
| 390 | How did Hershey and Chase prove that DNA is the genetic material? | 12 |
| 391 | Choose the correct answer from the alternatives given : If Meselson and Stahls experiment is continued for four generations in bacteria, the ratio of ( N^{15}-N^{15}, N^{14}- ) |
12 |
| 392 | The first amino acid in any polypeptide chain of prokaryote is always A. Formylated methionine B. Formylated arginine c. Lysine D. Methionine |
12 |
| 393 | Question 24. Write the important structural and functional differences between DNA and RNA. |
12 |
| 394 | If there are 120 adenine molecules in a B-DNA double helical structure showing 20 coils, what is the number of pyrimidine nucleotides forming three hydrogen bonds in it? ( A cdot 80 ) B. 100 ( c cdot 120 ) D. 140 |
12 |
| 395 | Differentiate (three) between DNA and RNA. |
12 |
| 396 | The structure of DNA is A. Linear B. Double helix C. single helix D. Triple helix |
12 |
| 397 | A mRNA coding for a secretory protein, when translated using free ribosome under in vitro conditions, resulted in a ( 40 k D a ) protein. The same mRNA when translated using the rough endoplasmic reticulum resulted in a ( 36 k D a ) protein. The difference in the molecular weight of the two polypeptides is due to the loss of a A ( .2 k D a ) peptide from ( N ) -terminus and a ( 2 k D a ) peptide from the C-terminus B. ( 1 k D a ) peptide from ( N ) -terminus and a ( 3 k D a ) peptide from the C-terminus C. ( 4 k D a ) peptide from the N-terminus D. ( 4 k D a ) peptide from the C-terminus |
12 |
| 398 | DNA differs from RNA in A. Nature of sugar alone B. Nature of purines alone c. Nature of sugar and pyrimidines D. All the above |
12 |
| 399 | Which of the following is characterized by the tightly coiled, condensed form of DNA that is not transcribed? A. Promoter B. Enhancer c. operator D. Euchromatin E. Heterochromatin |
12 |
| 400 | Which one of the following is wrongly matched? A. Transcription – Writing information from DNA to t-RNA B. Translation – Using information in mRNA to make protein C. Repressor protein – Binds to a operator to stop enzyme synthesis D. Operon – Structural genes, Operator and Promoter |
12 |
| 401 | What are the differences between DNA and RNA? |
12 |
| 402 | Purine base of DNA molecule has A. A and B. c and T c. A and a D. None of the above |
12 |
| 403 | What do you understand by the antiparallel arrangement of DNA strands? | 12 |
| 404 | Transfer of information from molecule of DNA to mRNA is called as A. Transcription B. Translation c. Replication D. None of the above |
12 |
| 405 | Formation of mRNA from DNA is called as A. Translation B. Transcription c. Transformation D. Transduction |
12 |
| 406 | Find the sequence of binding of the following amino acyl-tRNA complexes during translation of an mRNA transcribed by a DNA segment having the base sequence 3’TACATGGGTCCG5′. Choose the answer showing the correct order of alphabets. A. P, Q, s, в. Q, Р, s, c. Р, ( Q, ) R, D. Q, P, R, |
12 |
| 407 | The monomers of a polyribonucleotide are A. Deoxyribonucleotides B. Ribonucleosides c. Polypeptides D. Ribonucleotides |
12 |
| 408 | With the help of a neat and labeled diagram describe Waston and Crick’s model of DNA. |
12 |
| 409 | Peptidyl transferase plays an important role during protein synthesis. What is true about this enzyme? A. It is proteinaceous B. It is RNA as catalyst c. It helps in peptide bond formation D. Both B and C |
12 |
| 410 | What does lac refer to in the lac operon? A . Lactase B . 1,00,000 c. Lac insect D. Lactose |
12 |
| 411 | Balbiani rings are sites of which of the following? A. DNA replication B. RNA and protein synthesis c. synthesis of lipids D. Synthesis of polysaccharides |
12 |
| 412 | Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in protein synthesis or as ‘start’ or ‘stop’ codon? A . UCG – Start B. UUU – Stop c. UGU – Leucine D. UAC – tyrosine |
12 |
| 413 | Choose the correct answers from the alternatives given : Transcription involves A. synthesizing the protein on the ribosome B. transferring information contained in the DNA to mRNA c. joining amino acids by peptide bonds D. transferring information from the mRNA to tRNA |
12 |
| 414 | Question 22. What is the difference between a nucleoside and a nucleotide? |
12 |
| 415 | Briefly describe the following: (a) Transcription (b) Polymorphism (c) Translation (d) Bioinformatics |
12 |
| 416 | (a) In an experiment Griffith introduced heat-killed S-strain bacteria Streptococcus into a mouse along with live R-strain bacteria. The mouse died but the scientist recovered living ( mathrm{S} ) strain bacteria from the dead mouse Explain the conclusion Griffith arrived at after the experiment. (b) Explain MacLeod, McCarty and Averys work that followed Griffith’s experiment. State the conclusion they arrived at. |
12 |
| 417 | Explain aminoacylation of tRNA. | 12 |
| 418 | Which conserved motif occur in Escherichia coli genes? A. TATA box B. CAAT box c. Pribnow box D. None of the above |
12 |
| 419 | If the sequence if the nitrogenous bases on template strand is ATCTGGCGT, what would be the sequence of mRNA transcribed from it? A . AUCACCGCU в. UUcUGGCGU c. UAGACCGCA D. AUGUccGCU |
12 |
| 420 | Protein synthesis in an animal cell occurs A. On ribosomes present in cytoplasm, ER as well as in mitochondria B. On ribosomes present in the nucleolus as well as in cytoplasm. c. only on ribosomes attached to the nuclear envelope and endoplasmic reticulum. D. only on the ribosomes present in cytosol |
12 |
| 421 | Ribozyme is A. An enzyme, which helps in protein synthesis B. An enzyme, which joins thymine to adenine C. An enzyme, which helps in degeneracy D. Exceptional to eukaryotes |
12 |
| 422 | In nucleoside, the nitrogen base is attached to the first carbon of sugar by bond. A. Glycosidic B. Hydrogen c. Phosphodiester D. Phosphate |
12 |
| 423 | For every single amino acid incorporated in peptide chain ATP and GTP molecules are used. A ( cdot 1,4 ) B. 1,6 ( c cdot 1,2 ) D. 1, 3 |
12 |
| 424 | First strand of cDNA can be synthesized by A. Transaminase B. DNA ligase c. RNA dependent DNA polymerase D. DNA dependent DNA polymerase |
12 |
| 425 | Instead of ( 3, ) if it was 2 bases code for an amino acid, the degeneracy of codons coding for the same amino acid would have A. Increased B. Decreased c. Remained the same D. Been uncertair |
12 |
| 426 | Which conserved motifs are found in E.coli genes? A. TATA box B. CAAT box c. Pribnow box D. All of the above |
12 |
| 427 | Degeneracy of the genetic code denotes the existence of A. Multiple codons for a single amino acid B. Wobble hypothesis c. Base triplets that do not code for amino acids D. All of the above |
12 |
| 428 | What is the function of a non-sense codon? A. To release polypeptide chain from tRNA. B. To form an unspecified amino acid. C. To terminate the message of a gene controlled protein synthesis. D. To convert a sense DNA into non sense DNA. |
12 |
| 429 | After a mutation at a genetic locus, the character of an organism changes due to the change in which one of the following? A. Protein synthesis pattern B. RNA transcription pattern c. Protein structure D. DNA replication |
12 |
| 430 | The environmental factor that influences the elongation of polypeptide chain is A. Light B. Oxygen c. Humidity D. Temperature |
12 |
| 431 | Select the wrong statement A. Presence of chromogenic substrate gives blue colour colonies if the plasmid in the bacteria does not have an insert B. Retroviruses in animals have the ability to transform normal cells into cancerous cellsın microinjection, cells are bombarded with high velocity microparticles of gold or tungsten coated with DNA C. since DNA is a hydrophilic molecule it cannot pass through cell membranes D. DNA is a negatively charged molecule |
12 |
| 432 | Ribosomes are the site for A. DNA replication B. Transcription c. Translation D. Translocation E . Repression |
12 |
| 433 | Which site of the RNA pairs through hydrogen boding with the triplet codes on mRNA? A. codon B. ( 5^{prime} ) end of tRNA c. ( 3^{text {‘ end of tRNA }} ) D. Anticodon E. Amino acid acceptor end |
12 |
| 434 | The codon for anticodon 3′-UUUA-5′ is A. ( 3^{text {‘-AAU-S }} ) B. 5′-UAAA-3′ c. 5′-AAAU-3 D. 3′-UAAU-5’ |
12 |
| 435 | In a double-stranded DNA, the sequence of base pairs in one strand is AGCTAAGC. What is the complementary sequence on the other strand? |
12 |
| 436 | Which of the following is initiation codon? A . AUGGGGGGGGG ( . ) GGGGG B. AUU c. UAG D. uvu |
12 |
| 437 | 138. Adenosine is an example of (a) purine base (b) nucleoside (c) nucleotide (d) pyrimidine base. |
12 |
| 438 | Explain the steps involved in translation | 12 |
| 439 | Out of the following statements, which one is true? A. DNA is single stranded, RNA is double stranded B. There is only one type of RNA, whereas there are many types of DNA. c. DNA synthesizes RNA, but RNA generally cannot synthesize DNA. D. DNA bases are adenine, guanine, cytosine, uracil and RNA has adenine, guanine, cytosine, thymine |
12 |
| 440 | Double helix model of DNA was proposed by A. Nirenberg B. Komberg c. Holley and Nirenberg D. watson and Crick |
12 |
| 441 | RNA is more reactive than DNA. Why? | 12 |
| 442 | Which one is correctly matched with its specificity for an amino acid, start or stop in protein synthesis? A. UCG – Start B. UUU – Stop c. UGU – Leucine D. UAC – Tyrosine |
12 |
| 443 | ( mathbf{A} ) ( 340 A ) long segment of DNA molecule has 20 thymine nitrogenous bases, what will be the number of guanine nitrogen bases in the same segment? A . 10 B . 40 c. 80 D. 160 |
12 |
| 444 | Similarity between DNA and RNA is that both have A. Similar sugars B. Similar mode of replication c. similar pyrimidines D. Polymers of nucleotides |
12 |
| 445 | What is true for E. coli with lac-z gene? A. They cannot synthesize permease. B. They cannot synthesize functional beta galactosidase. C. They cannot synthesize transacetylase. D. They cannot transport lactose from the medium into the cell. |
12 |
| 446 | What is a genetic code? | 12 |
| 447 | Choose the correct answers from the alternatives given If the sequence of bases in DNA is TAGC, then the sequence of bases in RNA would be A . AUCG B. TAGC c. АТСС D. GCTA |
12 |
| 448 | In Drosophila, a set of homeotic genes which control body plan at the time of organ differentiation is known as A. TATA box B. Homeobox c. Pribnow box D. All of the above |
12 |
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